disturbed

having the place or position changed; "the disturbed books and papers on her desk"; "disturbed grass showed where the horse had passed"

afflicted with or marked by anxious uneasiness or trouble or grief; "too upset to say anything"; "spent many disquieted moments"; "distressed about her son's leaving home"; "lapsed into disturbed sleep"; "worried parents"; "a worried frown"; "one last worried check of the sleeping children"

emotionally unstable and having difficulty coping with personal relationships

affected with madness or insanity; "a man who had gone mad"