doom

an unpleasant or disastrous destiny; "everyone was aware of the approaching doom but was helpless to avoid it"; "that's unfortunate but it isn't the end of the world"

decree or designate beforehand; "She was destined to become a great pianist"

pronounce a sentence on (somebody) in a court of law; "He was condemned to ten years in prison"

make certain of the failure or destruction of; "This decision will doom me to lose my position"