pain

a symptom of some physical hurt or disorder; "the patient developed severe pain and distension"

emotional distress; a fundamental feeling that people try to avoid; "the pain of loneliness"

a somatic sensation of acute discomfort; "as the intensity increased the sensation changed from tickle to pain"

a bothersome annoying person; "that kid is a terrible pain"

something or someone that causes trouble; a source of unhappiness; "washing dishes was a nuisance before we got a dish washer"; "a bit of a bother"; "he's not a friend, he's an infliction"

cause bodily suffering to and make sick or indisposed

cause emotional anguish or make miserable; "It pains me to see my children not being taught well in school"